CANTUZUMAB RAVTANSINE
Cantuzumab ravtansine is an antibody drug conjugate pharmaceutical. It is currently being investigated in clinical studies. It is known to target mucin-1.
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Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
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YTD
1Y
2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | — | — | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CANTUZUMAB RAVTANSINE |
| INN | cantuzumab ravtansine |
| Description | Cantuzumab Ravtansine (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies; maytansinoid derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1742998 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | RNQ8JQ4R9P (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
MUC1
MUC1
Organism
Homo sapiens
Gene name
MUC1
Gene synonyms
PUM
NCBI Gene ID
Protein name
mucin-1
Protein synonyms
Breast carcinoma-associated antigen DF3, CA 15-3, Cancer antigen 15-3, Carcinoma-associated mucin, CD227, EMA, Episialin, H23 antigen, H23AG, KL-6, Krebs von den Lungen-6, mucin 1, transmembrane, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Uniprot ID
Mouse ortholog
Muc1 (17829)
mucin-1 (Q02496)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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